Active rh TGF β-3 – RF004

  • Product under demand. Please contact us directly at: info@agrenvec.es
  • Description: Active human TGF β-3
  • Application: BIOASSAY, SDS-PAGE, WB
  • Alternative Names: Transforming growth factor beta-3; TGF-beta-3
  • UniProtKB: P10600
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Description

Molecular weight: 27.2 kDa protein composed of two identical 118 amino acid polypeptide chains linked by a single disulfide bond.

Description:Transforming growth factor –β is a family of five related cytokines that have been shown on a wide variety of normal and neoplastic cells, indicating the importance of these homodimeric proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGFβ (TGFβ-1, TGFβ-2 and TGFβ-3) signal through the same receptor and elicit similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodelling and wound healing.

Biological Activity: The biological activity of TGF-β3 is measured in culture by its ability to inhibit the mink lung epithelial (Mv1Lu) cells proliferation.

Coomasie-TGFB-3-181x300
Figure 1. SDS-PAGE analysis of recombinant TGF β3. Samples were loaded in 15% SDS-polyacrylamide gel and stained with Coomassie blue. Lane MWM: Molecular weight marker (kDa); lane a: contains 0.2 ug of recombinant TGF β3. (reducing condition, ~13kDa monomer and ~26kDa homodimers)

Human recombinant protein expressed in Nicotiana benthamiana.

Bulk sizes are available upon request.
For R&D purposes only. Purchaser must determine the suitability of the product(s) for their particular use.

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